Question
With 4 points invested, deadliness gives .5 dmg per level. Thats 9 extra damage at level 18. Many runes do something similar, (very small per level bonuses). Are bonuses of this nature actually worthwhile in any way? I don't see how 9 extra damage endgame is going to matter. (Exceptions made for the magic resist and cooldown reduction versions of these bonuses as their endgame final addup is easily viewed as worthwhile)
Answer
The Deadliness masteries gives 9 points of damage at character level 18. Think of it as a free Longsword
It does not seems a lot, but it represents more than a 3% AD increase on most fully geared AD carries or bruiser, as neither is nowhere near 300 AD, which is quite efficient, as far as masteries go.
To compare, assuming you go into Utility tree deep enough to grab the Greed masteries, you'd need no less than 34 minutes and 10 seconds for the Greed Masteries to pay for the free Longsword, without even taking into account inventory room and power gain through your leveling.
Not only are the Deadliness masteries efficient, but they are compulsory on attack characters. AD / level runes, on the other hands, are dubious. Take either Flat AD or Armor Penetration.
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