How can I clear gaps in the Binding of Isaac?

Question

I have coins. I have bombs. I lack keys and health. Obviously means I found a key and a heart pickups; they're so close, and yet so far.

Now, I know one of the devil pacts grants you flight. Is that the only way to reach those areas?

Answer

You can get the following pickups to cross gaps:

• Ladder - Cross 1 gap spaces
• Demon Form - Gives you the permanent ability to fly (not sure what the exact pickup name is)
• Hanged Man Tarot Card - Gives you the ability to fly for your current room only

Credit to Chris Rasys for mentioning the Magnet, which can pull items towards you from a short distance away. While not technically the same as crossing the gap, it serves the same effect for the purpose of retrieving unobtainable items.

In this case, where there's a rock right next to the gap, using a bomb will plug the hole. This appears to be fickle though, as I've had bombs just destroy the block and not plug the hole. It appears that you have to be pretty precise in terms of the bomb placement so that the blast is exactly horizontal/vertical to the block.

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